You can't tell these folks what to do. You can't say "Stop drinking at 7 AM and put away the crack pipe." or "Take this psychotropic medicine that makes you feel weird 3 times a day with food." and expect them to comply since they have no reason to do it. Only by forcing them into treatment could a difference be made, and that isn't going to happen. Talk to some of these folks. Most of them can't even stay clean unless they are institutionalized.